Buy MOTS-c in the UK
The first identified mitochondrial-encoded signalling peptide — encoded inside the mitochondrial 12S rRNA gene rather than the nucleus. Available in 10 mg lyophilised vials, HPLC-verified, with same-day dispatch and 24-hour delivery UK-wide.
- HPLC-verified, lot-level COA
- Same-day dispatch before 4 PM London time
- 24h delivery to London, Manchester, Birmingham, Glasgow
- 24–48h to Sheffield, RAK, Liverpool
- Crypto or Card via Whop UK-wide
- Free shipping over £100

The science in one paragraph
MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA-c) is a 16-amino-acid peptide identified by the Pinchas Cohen lab at USC in 2015. Unlike every other peptide on this site, MOTS-c is encoded inside the mitochondrion — in a small open reading frame nested within the mitochondrial 12S rRNA gene. It activates AMPK, increases glucose uptake into skeletal muscle, and reduces insulin resistance in mouse models on high-fat diet. Full mechanism in our research guide.
What the literature documents
Lee 2015 (Cell Metab) — foundational discovery paper. AMPK activation, insulin sensitisation, weight gain reduction in HFD mice.
Reynolds 2021 (Nat Commun) — MOTS-c levels rise with exercise and fall with age. Administration rescued running capacity in aged mice.
Kim 2018 (Cell Metab) — MOTS-c translocates to the nucleus under metabolic stress and binds transcription factors directly.
Vial in UK inventory
UK delivery to your region
Buy MOTS-c UK — FAQ
REVIVE LAB UK supplies MOTS-c UK-wide. Same-day dispatch, 24h delivery, Crypto/Whop available.
10 mg lyophilised, HPLC-verified, COA on every parcel.
No published RCT of exogenous MOTS-c in humans. Plasma-level data only.